Half Lives

April 3rd, 2008

All testosterone is active immediately upon injection. Half life refers to the time it takes for your body to metabolize the product and dispose of the chemical remains of half of the substance.

A lot of people are confused about this.

The question is then why use different products?

The reasons are as follows:

  1. Mg for mg, short acting esters contain more product than longer esters.
  2. Stable blood levels are easier to achieve while using the frequent dosing required by short acting esters.
  3. Short acting esters are best when on a short duration cycle or when you need the ablility to stop effects quickly (cutting)
  4. Longer esters are desireable when bulking because they exert their influence on the androgen receptors for a longer period of time.
  5. Longer esters allow you not to feel like a pin cushion
  6. Lengthy cycles are easier with long acting esters.

All types of test have their pros and cons.

Any form of test with a half life of 7 days or longer is a long acting form and little difference is seen between 7 to 12 days half life.

All test kicks in immediately, but the noticable effect is signaled by the conversion of test either via the dht pathway or the estrogen pathway.

In other words, the reason some drugs "kick in" more quickly is because, they are unbound from their ester and converted or metabloized more quickly than other drugs. You feel aggresive and more intense because the dht receptors are activated because the short acting test has been metabolized. Still the masculizing effects of testosterone begin at the moment that the esterfied testosterone molecule binds with an androgen receptor. So the increase in protien synthesis begins immediately no matter which form of test you inject.

Test is test. Now, how long it will continue to act is an entirely different concept. Longer acting esters create longer acting effects. Less frequent injections allow us to maintain similar ammounts of free testosterone in the bloodstream. Many of us do 400 to 700 mgs of prop each week. We do 500 to 700 mgs of enth or cyp each week.

If you do the math on how long the half life of each product is you’ll find that you actually carry higher levels daily with longer acting esters, which is why we use them to bulk. Shorter acting esters provide a quick conversion to dht which causes hardening of the muscles and a leaner overall look, which is why we use them to cut.

There is another point here.

New users of test products should understand that testosterone in any form shuts down the hypothalmic/testicular/pituitary axis (htpa for short). How much you take and for how long will determine how hard you shut it down and how long it may take to recover.

We all have a certain ammount of androgen receptors in our bodies. As the testosterone increases, the body produces new receptors. However this is not a rapid process. In fact it can take months for the body to produce enough receptors to be able to use all of the testosterone that is injected. This is why more is not always better.

Say if you have enough receptors to use 250 mgs of testosterone, any more that you inject will simply be broken down without binding to any androgen receptor and converted to dht or estrogen without exerting any effect on the muscles. This does not mean however, that it will not affect the htpa. It will shut down the htpa without any positive benefit for the user.

When you see that certain mods and vip’s are using high ammounts of test (above 750 mgs/week) realize that we’ve been cycling aas for years and we’ve build up enough receptors to use that ammount of gear. Also realize that many of us have come close to ruining our htpa permanently at one point or another.

Rhae

The Whole Story

March 26th, 2008

Here it is, the whole story; a fiction that contains a wealth of information about every aspect of progressive bodybuilding. Do you want to learn more about how to train in the gym, increasing your poundages in order to become stronger and bigger? Do you want to learn more about nutrition and rest – the keys that unlock the door to strength and size gains? If so, read on, because its all here. Oh, and if you read on you’re going to find detailed information about steroids. This story will help you decide whether you should consider using steroids, and/or how exactly you should use them. Don’t expect anything to rival Shakespeare, but this is good stuff…

So it was 1999, the year 2000 was about to dawn. In the eastern side of a city in the north of England old factories lay empty, remnants of an industrial past. Most houses were terraces built around 1900, with the original Victorian fireplaces and plasterwork on the ceilings. The men would have worked in the steel factories if they hadn’t closed. Now the women had begun working in warehouses or on tills in supermarkets, to make ends meet. Everyone – men and women – had to acquire new skills and grasp for new and different job opportunities. Not everyone was up to the task.

Two young men, Pete and Steve, had grown up together in the area. They were old enough to vividly remember the mass redundancies twenty years before; they had seen men turn to drink while their families went without. Pete and Steve wanted something better, so they chose college over second rate jobs or unemployment. At the same time they chose to spend their free time in an old damp gym, housed in small disused warehouse, instead of going to the pub. College by day – Pete wanted to teach, while Steve saw opportunities in IT – and gym by night. It seemed like good ‘clean’ living, and it felt good to be free of the unhealthy lifestyles – involving smoking and junk food, as well as alcohol – that so many of their contemporaries fell into without thinking. For fun they usually chose active pastimes, such as hiking in the local Peak District national park, five-a-side soccer with friends, or they’d bring their girlfriend’s along for a game of doubles tennis at the local – council subsidized, thank God – leisure centre.

The other side of the city, on the west, was very different. Alongside wide streets were large detached houses, belonging to doctors, lawyers, and accountants. Neat front gardens bordered the clean driveways of these houses, which tended to be occupied a father’s large executive saloon, a wife’s sporty runabout, and a third expensive vehicle belonging to a grown up son or daughter. A large park was never far away. For the people living in this area almost any purchasable item could be acquired with the flick of a credit card. But money couldn’t buy everything, as a young man called Dan, who’d grown up in the area, knew well. You see Dan was never really happy with himself, or his looks, and simply being born rich didn’t make him feel worthwhile as a person or as a man. He began using strength training machines at a local health club.

Pete and Steve never met Dan. After graduating from college they were earning decent money, but they had no interest in joining Dan’s club. After all, Pete and Steve had no use for a pool, sun-beds, and comfortable toning machines. The fact is that when it came to training, they were the lucky ones. Their gym was owned by a weathered lifetime bodybuilder, still rock hard and strong as a bull in his 60s; someone who had trained countless bodybuilders and boxers for competition. They had a mentor to tell them what bodybuilding was about: progressive poundage increases in a few big multi-joint lifts, eating lots of natural food, and resting. They were in the gym only three times per week (upper body push Monday; lower body Wednesday; upper body pull Friday), but they trained hard and added cardio-vascular exercise at least two times per week. Six exercises – squat, deadlift, chin, row, dumbbell chest press, and overhead press – formed the core of their routine. Meanwhile Dan was straining away on his pec-deck, his machine curls, and his leg extensions.

When they started Pete and Steve were squatting less than 100lbs for 15 repetitions, but every week without fail they added a little bit of iron. Just 2lbs on extra on the bar most weeks, but up to 5lbs just occasionally, when they felt unusually strong. Sure, it seemed slow, but after two years they were squatting 310bs for 15 repetitions, and they both had thick and strong legs. All their other lifts had gone up as well. Dan, in contrast, had nothing but increasing frustration to show for his two years of training. He had toned up a little, and people who looked closely may even have noticed a very slight weight gain, but he wanted to stand out, and look strong. He didn’t realise that in order to be strong he had to incorporate ‘big’ muti-joint exercises, like the squat, the deadlift, heavy upper body presses, and heavy pulls. He wasn’t really lifting, and he wasn’t really eating.

Dan was spending a fortune on deliciously flavoured (or so the adverts claimed) meal replacement drinks and snack bars. He bought weight gainers promising HUGE muscle gains in very short timeframes, containing apparently wondrous substances such as “testomax” and “androprotein complex”. Little time was “wasted” on real food. It never occurred to Dan that the processed milk proteins in meal replacement bars might be denatured, and difficult for his body to tolerate. He never researched the subject of nutrition enough to learn that the corn syrup in such bars can bring about insulin reactions which can be associated with fat gain or even diabetes. Finally, he knew that his protein drinks were sugar free, but he didn’t know that the chemical sweetners they contained could be a health risk (aspartame has been linked to migraine, stomach problems, and even multiple sclerosis!). He’d have done so much better if he had eaten a few steaks for protein – there would have been added benefits such as iron, vitamin B12, co-enzyme Q-10, and creatine.

Pete and Steve could have taught Dan a thing or two. Every evening they prepared six meals to consume the following day. They understood that to keep their bodies in an “anabolic” growth-mode they required concentrated sources of protein, like meat, fish, or eggs; they knew that complex carbohydrates (obtained from wholewheat rice or bread, kidney beans, and pasta) are stored within muscle, in the form of glycogen, ready to fuel muscular contraction (by replenishing ATP) during intense workouts; when they ate their vegetables they did so with an appreciation of the detoxifying qualities of antioxidants; they took on board their good fats and essential fatty acids (in fatty fish, avocado, olive oil, nuts, and unrefined vegetable oils) for hormonal health, nerve health, mental health, and to maintain a good cholesterol profile. It was also important to avoid what was bad: Pete and Steve knew that they had to avoid simple forms of sugar, because excess sugar is taken from the blood by insulin and turned to fat by the liver. They avoided hydrogenated vegetable fats (associated with heart disease and cancer) like the plague.

A year passed, and although he was still in the gym six days per week Dan had lost his enthusiasm. Several injuries were bothering him, because he wasn’t aware of the importance of good exercise form or proper recovery. Now cynical about training (and, to be honest, about life) he was finally awakened to the fact that flashy supplements are no more help than the “get big quick” routines set out in muscle magazines. By this point he just didn’t believe that a good physique could be developed by an ordinary guy like him – not without drugs. He’d done his best, or so he thought, and so he saw nothing but so much wasted effort. It was tempting to give up, and replace time in the gym with time on the golf course, unless…

Dan decided to take a gamble. In quiet moments at work he sat at his computer, secretly looking up different online suppliers of steroids. What a lottery: which suppliers are legitimate? Are any legitimate? Dan didn’t know who to trust, and he didn’t take the time to find out – he wanted, no needed results fast. “To hell with it”, he thought, and placed an order. Instead of dianabol only – his first thought since he didn’t fancy needles, and as such orals had seemed like the ideal solution – he went for dianabol and deca-durabolin. That was the mainstay of the cycles famous pros did in the ‘70s, or so he’d read, so he reasoned that it must be good enough for him. He had taken a brief look at injectable testosterone, but he noticed that it was inexpensive, and in his world inexpensive and bad were the same thing.

After completing their third year of serious training Pete and Steve were anything but frustrated. Pete was under strain, since he was taking home extra work to help the less advantaged students in his classes, and Steve was working long hours for a software development company. Nevertheless, their training was unaffected while they were eating well and allowing enough rest days between workouts. Progress had slowed for sure, and a couple of injuries had held things up, in spite of their impeccable training form. But they were adding 2lbs to their squat every other week, and by this point other guys in the gym looked on with respect when they saw squats with 340lbs for 15 clean and deep reps. They had achieved this though patience, and consistency, and through their willingness to get back in the gym every week, always striving to add just a tiny bit of iron to their core lifts. They knew how a person’s true metal in a gym is tested; they knew what training is all about: training, like life, is about hard work, and sustained self-belief, and progress that is so gradual that can seem imperceptible – it takes so long and the end seems distant, but the secret is to never give up trying.

For Pete and Steve there was no need to take steroids – or no need to rush into it at any rate. Nevertheless, with a view to reaching their own conclusions, and taking informed decisions, they did research the subject at length (although learning still more about diet and training methods remained a higher priority). Sure, it was tempting to accept steroid rumours and hype without question; it was tempting not to think about the risks and complications. The prospect of making big gains fast, going to bed a Stallone and walking up an Arnold or a Dorian, was tantalizing. And yet sense prevailed. After all, Pete and Steve knew too well that every aspect of the bodybuilding game – not just drug use – is rife with misinformation, needless complication, and ignorance. They distrusted hyped up supplements, and all new ‘periodized training protocols’, and in the same way
they weren’t going to believe that injecting synthetic hormones could ever be a substitute for years of hard work in a squat rack.

In the end Steve chose to use steroids, and Pete did not. Their training partnership and friendship was as strong as ever, but their priorities diverged a little. Pete felt good, looked good, and he knew he could maintain his condition and continue adding little bits of weight to the bar without gear. He wanted to keep things simple, and he’d earned the right to feel satisfied with what he had – what he’d worked so hard for. To keep things interesting he could continue to set himself meaningful targets, such as to squat twice his body weight for reps or achieve a 20-rep chin. Entering a strong man competition was something Pete planned to try at some stage, and he was also up for giving an all-natural bodybuilding contest a go. But he was fine with Steve’s choice, and that of any responsible adult who knew how to use steroids in a way that maximizes effectiveness and minimises risk. As for Steve, he wanted to keep pushing at the barriers of what was possible; he wanted to see how far he could go.

By this time Dan had been popping dianabol tabs and injecting “deca” for some time. Sure, he had gained weight, but he wasn’t feeling good. His face was swollen, and his nipples were itchy, and very tender. Unfortunately he didn’t know Steve, who could have told him about estrogens and progestins – products of the dianabol and the deca. Estrogens, important hormones for women, and progestins (which stimulate the production of progesterone, another hormone in women) were causing him to retain water, encouraging fat gain, and having a feminising effect on the mammary glands in his chest. A low dose of a simple drug to block estrogens (tamoxifen) or a drug to prevent the conversion of dianabol to estrogens (e.g. arimidex) would have solved the problem – possibly alongside a drug to control prolactin (e.g. bromocriptine).

Steve was in the process of decorating his house, so it was a mess, but he kept his desk tidy where he read from a pile of books about anabolic steroids. A friend of his worked at a University library, so he’d even managed to get hold of some medical texts. He needed to know how natural hormones work before he could appreciate the action of steroids – synthetic hormones. He learned how the body registers how much testosterone it has it its system, and how it stops making testosterone when steroids are used: When a man is steroid free messages are sent to the hypothalamus, telling it that normal amounts testosterone are bound to androgen receptors in the cells, and levels of estrogens are normal. When necessary the hypothalamus reacts to maintain stable testosterone levels by making GnRH, which tells the pituitary gland to get to work. The pituitary then makes “LH” (Luteinizing hormone) and “FSH” (Follicle-stimulating hormone), which instruct the testes to make testosterone and sperm. The process breaks down when steroids of any variety bind to the androgen receptors, and the body sense raised levels of estrogens. At this point the body recognises that it has too much testosterone, or more than it thinks it needs.

Fair enough, thought Steve, ‘so my body will temporarily stop making its own testosterone while I’m on gear – not a problem so long as the steroids I am administering are performing all the functions of natural testosterone during that time…’. And yet Steve soon realised that there is a potential problem, given that only one steroid performs all the functions of natural testosterone – synthetic testosterone. Good job Steve had learned that, because if he had, for example, taken Nandrolone on its own it would have stopped his natural testosterone production without performing the sex related functions of testosterone. Steve had a fit girlfriend to keep happy – damn it, he was hoping to get engaged! In any case, because of its dual androgenic and anabolic effects, and superior mass building properties, Steve knew that he’d be making testosterone the cornerstone of his steroid use. That way he would get better results in the gym, and in bedroom. Sure, he might use a drug like nandrolone when he became more advanced, but always alongside testosterone.

Another key question on Steve’s mind related to how much time he should stay on steroids before taking a break, and how long breaks should last. Sure, he had known guys who used gear most of the year, but nearly all of these clearly didn’t know what they were doing, and they didn’t even look good. They were wrecking their health, fertility, and virility. He knew only one properly clued up guy who stayed on most of the year – a very gifted and very experienced 300lb man, who was hoping to win the British Championships. But Steve’s situation was very different, and since there was no immediate prospect of his gaining lucrative sponsorship from supplement companies, or becoming a pro, then staying on gear for extended periods was never going to be worth his while.

Ultimately since he wasn’t going to take risks without good reason, Steve knew that he needed to use steroids in “cycles” – a “cycle” being a limited time period in which goals are achieved (e.g. realistic strength or mass gains, or fat loss). Post cycle he would have to stay off all steroids for extended periods while his cholesterol profile, blood pressure, and natural hormone production returned to normal (with the help of good dietary habits, and cardio-vascular exercise). He would have to kick of this off period with ‘post-cycle therapy’ – that is, he would administer drugs and supplements (nolvadex/timoxifen, and tribulus) which would stimulate his natural hormone production.

Steve moved on to learn more about how different steroids worked, and about their different side effects. Dan was experiencing gynaecomastia, water retention, and liver toxicity, without even knowing it or taking steps to minimise the risk – Steve wasn’t going to do the same. After all, he knew (as noted above) that it was important to have a drug like nolvadex or arimidex to hand when using any steroid that can convert to estrogens (notably Testosterone, as well as orals like Dianabol). Also, although he had been attracted to oral steroids at first – perhaps everyone new to steroids is, because the prospect of injecting can seem daunting – it wasn’t long before he understood that the way orals are altered to enables them to pass through the liver (they are 17 alpha-alkylated), often causes them to raise liver enzymes to an unhealthy level. So Steve, unlike Dan, was not going to be using Dianabol for longer than four weeks (six weeks max). Nevertheless, a little more research revealed that anavar and primobolan – comparatively mild orals – are exceptions, best used for longer periods either to support fat loss or to achieve small but lean muscle gains.

There was so much information to take in! For example, Steve began to see that if drugs are taken in combinations they can enhance the effect of each other – certain drug combinations are synergistic. Looking at Testosterone more closely, Steve learned that it is more effective when used alongside drugs that bind to Sex-Hormone Binding Globulin (SHBG) – the DHT derived drugs drostanolone (e.g. Masteron) and masterolone (Proviron). If another drug is binding to SHBG then testosterone has less opportunity to do so, which means that more testosterone remains unbound or “free”; and only “free” testosterone is able to enter a cell and activate it’s receptor. Unfortunately as good as this sounds there are always side effects to consider, with all injectables as well as with orals. For example, DHT isn’t good (DHT from DHT-derived steroids, and DHT that is a product of Testosterone – Testosterone converts to DHT). Problems for the prostate (benign prostate hyperplasia) and the scalp (hair loss) are associated with DHT. But there are ways to limit the risks: 1mg Finasteride per day, for example, can be a useful preventative measure, because it inhibits the conversion of Testosterone to DHT.

Steve kept pushing forward, dredging up information on side effects he didn’t really want to see, because he knew that he had to go in with his eyes open, fully prepared. Raised blood pressure was clearly another concern with many steroids, but he learned that he might be able to keep that in check by keeping his dosages down, by drinking lots of water, and by taking one harmless aspirin each day. Then there were issues with cholesterol, since steroids tend to lower ‘good’ (HDL) cholesterol, and raise ‘bad’ (LDL) cholesterol. Ideally the good stuff (HDL) mops up the bad stuff (LDL), preventing it from being deposited in arteries where it can eventually cause obstruction. So a less favorable HDL-to-LDL ratio isn’t good. Fortunately Steve knew that eating lots of good fat would help counteract that problem, and raise his HDL cholesterol, as would adding cocoa to homemade blender drinks. His dedication to cardio-vascular training – usually jogging with Pete, or walking with his fiancée – would help a lot too.

Mid-way into his fifth year of training Steve was ready to hit his first cycle, with Pete there to support him all the way. As a final bit of preparation he had attended a number of bodybuilding shows, and made opportunities to talk to successful bodybuilders – and steroid users – he respected. Once Steve got to know these guys they were happy to advise him, and (no messing) they told him to steer clear of excesses and harmful practices. A tried and tested ‘stacked’ cycle (a cycle containing more than one drug) was a real option for Steve, even though it was his first outing. After all, his body was advanced, and he really knew his stuff – he knew exactly what to expect if he took two drugs (e.g. Testosterone with Equipoise or Nandrolone), and exactly how to react if any problems arose. But in the end he saved the stacked cycle for eight months or so down the line, and started with something really simple – one steroid, Testosterone Enanthate, at 500mgs per week for 10 weeks. Why? Well, he was in no rush, and it was good science. This way he would be able to trace any effects back to one drug. Start with two drugs and how would know which one is effecting him, and how? Then next time around, if he felt different, he would know that the second drug was the culprit.

Pete remained steady, consistently lifting impressive weights after a hard day’s work teaching at a local school. Steve was just beginning to leave him behind, however, adding 5lbs to his squat each week with the help of the Testosterone he was injecting, and some extra food. What about Dan? Well, shit he was fed up. Six months after his much anticipated attempt to use steroids he had nothing to show for it but swollen nipples, shrunken testicles, and a serious loss of sex drive. Damn it, one of his primary reasons for using gear had been to attract women. Now when he saw a great looking girl he didn’t even want it – at least not really; not like he used to. Anyway, he was more insecure than ever now: what girl was going to want to see his swollen nipples and shrunken testicles?? At least he was beginning to figure our some of what he’d done wrong, although it had been months before he’d begun to think straight enough to analyze the situation. His first reaction, after coming off the Dianabol and “Deca” and seeing that it had been a disaster, had been to focus on feeling sorry for himself rather than to focus on the problem. He had even left his job, on the grounds that he was ‘sick’.

Soon after Dan began doing some reading he did, finally, recognize the extent to which he’d gone wrong, in every aspect of his training and steroid use. He came across reference to post-cycle therapy on the internet, and saw that 1000ius hcg per week for a short period would have got his nuts back into shape; nolvadex at twenty-to-thirty milligrams per day would have directly influenced his hypothalamus, which in turn would have stimulated his pituitary gland and finally his testes; tribulus – the natural supplement from plants – could have stimulated the andgrogen receptors in his brain; finally, an effort to obtain essential fatty acids (especially in fatty fish, or fish oil tablets) would have supported his natural hormone production when he most needed it. And Dan began the appreciate the mistakes he’d made with his training after he switched health clubs – he needed a new start! One day loud guy with huge legs, and lots to say against steroids, introduced himself to Dan; the guy encouraged Dan to check out a website and buy perhaps the best book on progressive bodybuilding ever written – Dan visited http://www.hardgainer.com/.

So as we draw to the end of our story, we leave Dan on the right track at last. Pete is drug free, although few who have seen him can believe it; he flexes his muscles on demand for his students, and his stature certainly affords him respect and credibility wherever he goes. Steve has finally decided to do just one steroid cycle per year most years – this way he has at least nine months of the year to get clear of side effects and give his natural hormone production every chance to rev back up to full tilt between cycles. After all, it seems to Steve that looking after his natural hormones will be the best way to stay consistent – energetic, virile, and strong, whether on or off cycle. Who knows, one day he might cautiously try human growth hormone, or IGF-1, should he want to step things up yet another level. But that’s unlikely – Steve is happy with himself provided he is lean, strong, and healthy, and for him bigger is not always better.

I hope all this shows how ‘real world bodybuilding’ – when there are barriers or even personal tragedies to overcome – should (and should not) be done. Please go away and think about it, and learn from it, and go on to do more (and more) research. Do it right, stay safe, and keep gaining for many healthy years to come. You can be like Pete, and build a great physique by simply sticking to the fundamentals of progressive training and good dieting. That way you get none of the risk or hassle that may accompany steroid use. Otherwise you can do a Steve, and minimize any possible risk by not using steroids until you are truly ready – physically and mentally. But best not do a Dan – after all, I wrote this story so that you don’t have to learn the hard way.

SAMSON.

3 Way Shuttle

March 4th, 2008

Here is the shuttle:
creatine/protein/carbohydrate
TOGETHER IN COMBINATION AND SHUTTLED

A few words by ALR: Insulin suppressed cortisol release while inhibiting circulatory cortisol activity. It also increased androgen activity and down regulated SHBG. This resulted in an elevated plasma level of free unbound testosterone and lower cortisol levels/activity to inhibit androgen induced protein synthesis. So it obviously required very little endogenous or exogenous testosterone to stimulate anabolism.

Here is the study:

: Med Sci Sports Exerc. 2007 Nov;39(11):1960-8. Links
A creatine-protein-carbohydrate supplement enhances responses to resistance training.Cribb PJ, Williams AD, Hayes A.
Exercise Metabolism Unit, Center for Ageing, Rehabilitation, Exercise and Sport and School of Biomedical Sciences, Victoria University, Victoria, Australia.

PURPOSE: Studies attributing gains in strength and lean body mass (LBM) to creatine monohydrate (CrM) during resistance exercise (RE) training have not assessed these changes alongside cellular and subcellular adaptations. Additionally, CrM-treated groups have seldom been compared with a group receiving a placebo similar in nitrogen and energy. The purpose of this study was to examine the effects of a CrM-containing protein-carbohydrate (PRO-CHO) supplement in comparison with a supplement containing a similar amount of nitrogen and energy on body composition, muscle strength, fiber-specific hypertrophy, and contractile protein accrual during RE training. METHODS: In a double-blind, randomized protocol, resistance-trained males were matched for strength and placed into one of three groups: protein (PRO), PRO-CHO, or the same PRO-CHO supplement (1.5 g x kg(-1) body weight x d(-1)) containing CrM (Cr-PRO-CHO) (0.1 g x kg(-1) body weight x d(-1)). Assessments were completed the week before and after a 10-wk structured, supervised RE program: strength (1RM, three exercises), body composition (DEXA), and vastus lateralis muscle biopsies for determination of muscle fiber type (I, IIa, IIx), cross-sectional area (CSA), contractile protein, and creatine content. RESULTS: Cr-PRO-CHO provided greater improvements in 1RM strength. At least 40% of the strength improvements could be attributed to hypertrophy of muscle involved in this exercise. Cr-PRO-CHO also resulted in greater increases in LBM, fiber CSA, and contractile protein compared with PRO and PRO-CHO. CONCLUSIONS: In RE-trained participants, supplementation with Cr-PRO-CHO provided greater muscle hypertrophy than an equivalent dose of PRO-CHO, and this response was apparent at three levels of physiology (LBM, fiber CSA, and contractile protein content).

PMID: 17986903 [PubMed - indexed for MEDLINE]

(Contributed by Bronson)

Basic Supliment Info and Uses

March 4th, 2008

Protein
The Health Benefits of Protein and Whey Protein
Protein is an important nutrient needed by everyone on a daily basis. Protein is made up of essential and non-essential amino acids, which are the "building blocks" for healthy bodies. Protein has a number of different roles in the body including the following:
Repair body cells
Build and repair muscles and bones
Provide a source of energy
Control many of the important processes in the body related to metabolism
source-energy first feel the difference

Casein
Features and benefits: Casein has a strong anti-catabolic effect. You might describe casein as the "opposite" of whey. They’re both great proteins but they act quite differently from one another. Casein has a lower anabolic effect (31 percent versus 68 percent) when compared to whey. However, casein has a very profound anti-catabolic effect, meaning that this protein inhibits protein breakdown. This has profound implications for the proper use of casein.
source-Eas Nutrition

Cinnamon
Molecular mimic
The active ingredient in cinnamon turned out to be a water-soluble polyphenol compound called MHCP. In test tube experiments, MHCP mimics insulin, activates its receptor, and works synergistically with insulin in cells.
To see if it would work in people, Alam Khan, who was a postdoctoral fellow in Anderson’s lab, organised a study in Pakistan. Volunteers with Type 2 diabetes were given one, three or six grams of cinnamon powder a day, in capsules after meals.
All responded within weeks, with blood sugar levels that were on average 20 per cent lower than a control group. Some even achieved normal blood sugar levels. Tellingly, blood sugar started creeping up again after the diabetics stopped taking cinnamon.
The cinnamon has additional benefits. In the volunteers, it lowered blood levels of fats and "bad" cholesterol, which are also partly controlled by insulin. And in test tube experiments it neutralised free radicals, damaging chemicals which are elevated in diabetics.
source-New Scientist . Com

Vitamin c
This water soluble vitamin has a multitude of functions in the body. Vitamin C provides strong antioxidant protection, immune system support and connective tissue production and repair. All of these are of great importance to someone involved in consistent exercise. Vitamin C also appears to have the ability to attenuate the production of cortisol secondary to intense exercise. Cortisol is one of the main catabolic (meaning it breaks down tissues) hormones in the body. By suppressing cortisol production vitamin C changes the cortisol to testosterone ratio, thus creating a more anabolic (tissue building) environment in the body.
source-Fitness Pro Bodybuilding

Vitamin B6 - pyridoxine - information page
Vitamin B6, also known as pyridoxine is part of the B group vitamins and is water-soluble and is required for both mental and physical health.
Vitamin B6 - pyridoxine - is required for
Pyridoxine is required for the balancing of hormonal changes in women as well as assisting the immune system and the growth of new cells. It is also used in the processing and metabolism of proteins, fats and carbohydrates, while assisting with controlling your mood as well as your behavior. Pyridoxine might also be of benefit for children with learning difficulties, as well as assisting in the prevention of dandruff, eczema and psoriasis.
It assists in the balancing of sodium and potassium as well promotes red blood cell production. It is further involved in the nucleic acids RNA as well as DNA. It is further linked to cancer immunity and fights the formation of the toxic chemical homocysteine, which is detrimental to the heart muscle.
Women in particular may suffer from pre-menstrual fluid retention, severe period pains, emotional PMS symptoms, premenstrual acne and nausea in early pregnancy. Mood swings, depression as well as loss of sexual drive is sometimes noted when pyridoxine is in short supply and the person is on hormone replacement therapy or on birth control pills.
source-Zest for Life

Vitamin B12 - cyanocobamin - is required for
Cobolamin is needed in the manufacture of red blood cells and the maintenance of red blood cells and it stimulates appetite, promotes growth and release energy. It is often used with older people to give an energy boost, assist in preventing mental deterioration and helps with speeding up thought processes. Some people are also of the opinion that it helps with clearing up infections and provide protection against allergies and cancer. This vitamin is also used in the metabolism of fats, proteins and carbohydrates.
source-Zest for Life

Vitamin E - tocopherol- information page
Vitamin E has earned itself a reputation - from spicing up your sex life to banning wrinkles and old age. One of the most important functions of this vitamin is its antioxidant properties. Vitamin E is an essential fat-soluble vitamin that includes eight naturally occurring compounds in two classes designated as tocopherols and tocotrienols.
Vitamin E is an effective chain-breaking, lipid-soluble antioxidant in biological membranes, and aids in membrane stability.

Vitamin E is required for
Vitamin E is a powerful antioxidant, protects your cells from oxidation, and neutralizes unstable free radicals, which can cause damage. This is done by the vitamin E giving up one of its electrons to the electron deficient free radical, making it more stable. While Vitamin E performs its antioxidant functions, it also protects the other antioxidants from being oxidized.
This antioxidant capability is then also great in helping to prevent degenerative diseases - including heart disease, strokes, arthritis, senility, diabetes and cancer. It also assists in fighting heart disease and cancers and is essential for red blood cells, helps with cellular respiration and protects the body from pollution - especially the lungs. Vitamin E is also useful in preventing blood clots from forming and promotes fertility, reduces and/or prevents hot flushes in menopause. An increase in stamina and endurance is also attributed to Vitamin E.
Vitamin E is also used topically to great effect for skin treatments - in helping the skin look younger, promoting healing and cutting down the risk of scar tissue forming. Used on the skin it is also reported to help with eczema, skin ulcers cold sores and shingles.
source-Zest For Life

Multivitamin/Mineral
For the human body to perform at its maximum potential, it must be fed a vast and complex array of vital nutrients. Becoming deficient in just one of these essential vitamins or minerals breaks down the metabolic pathway that produces optimum efficiency and performance declines. Not good! Daily consumption of a high-potency multivitamin/multimineral formula may help ensure the presence of essential cofactors necessary for thousands of metabolic reactions.
source-bodybuilding . com

Creatine
There is one good reason why three out of four of the ‘96 summer Olympic medallists used creatine: it works and it works well. A French scientist first discovered creatine in 1832, but it was not until 1923 that scientists discovered that over 95% of creatine is stored in muscle tissue. The first published report of creatine having bodybuilding effects was The Journal of Biological Chemistry in, get this, 1926! Although we’ve known about creatine for quite some time, the first real use of it to enhance performance was the 1992 Olympic games in Barcelona, Spain.
source-bodybuilding . com

BCAA’s
What are they?
The branched-chain amino acids (BCAAs) are leucine, isoleucine, and valine. BCAAs are considered essential amino acids because human beings cannot survive unless these amino acids are present in the diet.
BCAAs are needed for the maintenance of muscle tissue and appear to preserve muscle stores of glycogen (a storage form of carbohydrate that can be converted into energy).1 BCAAs also help prevent muscle protein breakdown during exercise
source-www. vitacoast . com

-Bronson

IGF Explained

February 25th, 2008
1: Type- IGF-1 Long R3 (Anything else is not as effective, and if the person providing it for you doesn’t know anything about it, you are asking for trouble.)
2. Storage- the most popular (and most effective) way to store, transport, preserve IGF is by suspending it in sterile BA in a sterile vial.
This will keep your IGF 99% potent for many months at a time in just about ANY indoor storage, I.E.-closet, drawer, etc.
3. Use- Usage should not exceed 4-5 weeks, and an OFF period should be about the same. Daily dosages work best (split up into 2 seems to make little difference in the Long R3 version) Most people see results at about 40mcg/day, some use as low as 30mcg/day, and some folks even use 80-100mcg. I SUGGEST to ALL first time users no matter what level, to start at about 40-50mcg/day.
4. Administration- I believe in IM injections over sub q, but either seems to be effective. I like IM better because IM using a slin pin is probably the least painful thing one could imagine, even at two times per day. Also, sub Q shots that contain BA, even diluted BA, can leave little nodules that you may not want to feel on your stomach.
5. Mixing- Most IGF comes suspended in BA. Hopefully it is @ 500mcg/ml or even 333mcg/ml (that would be at 2ml/mg and 3ml/mg respectively) Draw out your desired amount and back load a slin pin. Add enough Bacteriostatic Water to fill the U100 syringe completely.
Some inject immediately before training, while others choose to do 2 shots spread throughout the day… THEY BOTH WORK WELL. Try both; see which method makes your muscles pop out of your skin.
6. Add plenty of protein, and don’t shy away from carbs immediately after training. I used up to 100g of carbs after training, and my body fat went down, all without cardio.

The conversion rate of GH is more like 1 iu gh = 4-6 mcg of igf-1.

If this is true (and let’s pick 5mcg for an avg), 30mcg of igf = 6ius of GH. I’ve done enough GH to comment that it may be slightly better than this. The only bad thing is that it stops working in 4-6 weeks. Then you have to take the same time off as you were on before starting again. It has something to do with how the IGF was modified to produce the "long" version and your body eventually figures it out.

What is IGF??

IGF stands for insulin-like growth factor. It is a natural substance that is produced in the human body and is at its highest natural levels during puberty. During puberty IGF is the most responsible for the natural muscle growth that occurs during these few years. There are many different things that IGF does in the human body; I will only mention the points that would be important for physical enhancement. Among the effects the most positive are increased amino acid transport to cells, increased glucose transport, increased protein synthesis, decreased protein degradation, and increased RNA synthesis.

When IGF is active it behaves differently in different types of tissues. In muscle cells proteins and associated cell components are stimulated. Protein synthesis is increased along with amino acid absorption. As a source of energy, IGF mobilizes fat for use as energy in adipose tissue. In lean tissue,

IGF prevents insulin from transporting glucose across cell membranes. As a result the cells have to switch to burning off fat as a source of energy.

IGF also mimic’s insulin in the human body. It makes muscles more sensitive to insulin’s effects, so if you are a person that currently uses insulin you can lower your dosage by a decent margin to achieve the same effects, and as mentioned IGF will keep the insulin from making you fat.

Perhaps the most interesting and potent effect IGF has on the human body is its ability to cause hyperplasia, which is an actual splitting of cells. Hypertrophy is what occurs during weight training and steroid use, it is simply an increase in the size of muscle cells. See, after puberty you have a set number of muscle cells, and all you are able to do is increase the size of these muscle cells, you don’t actually gain more. But, with IGF use you are able to cause this hyperplasia which actually increases the number of muscle cells present in the tissue, and through weight training and steroid usage you are able to mature these new cells, in other words make them grow and become stronger. So in a way IGF can actually change your genetic capabilities in terms of muscle tissue and cell count. IGF proliferates and differentiates the number of types of cells present. At a genetic level it has the potential to alter an individuals capacity to build superior muscle density and size.

There is a lot of talk about the similarity between IGF and growth hormone. The most often asked question is simply which is more effective. GH doesn’t directly cause your muscles to grow, it works very indirectly by increasing protein synthesis capabilities, increasing the amount of insulin a person can use effectively, and increasing the amount of anabolic steroids a person can use effectively. GH also indirectly causes muscle growth by stimulating the release of IGF when it (the GH) is destroyed in the human body. So one way you could look at it as GH being a precursor to IGF. So to put it simple IGF is more effective at directly causing muscle growth and density increases. IGF is also much more cost effective.

IGF can also be effectively used by itself and gains will still be easily noticeable. With growth hormone you need to use high amounts of anabolics and often insulin to see any gains at all, this is not the case with IGF. IGF can be used by itself and is often used by bodybuilders who bridge between cycles, during this bridge is a good time to use IGF since it has no effect on natural testosterone production so it will therefore allow you to return to normal in terms of hormone levels. A stack of IGF, PGF2a, HCG, and clomid would be a good bridge stack and would allow your body to return to normal and still allow you to retain and make new gains.

IGF is a research drug, it hasn’t been approved by the FDA for use as a pharmaceutical and it is currently being researched for nerve tissue repair, possible burn victims, and also as a possible aid in muscle wasting for AIDS patients. There are many different analogs of IGF available, instead of mentioning them all, I will simply mention the two most common and the most effective. Regular recombinant IGF is one of the two, it is also the more expensive and the least effective. Regular IGF only has a half-life of about 10-20 minutes in the human body and is quickly destroyed, it can be combined with certain binding proteins to extend the half-life, but it is not a very simple procedure and there is a more effective and less expensive version available. The most effective form of IGF is Long R3 IGF-1, it has been chemically altered and has had amino acid changes which cause it to avoid binding to proteins in the human body and allow it to have a much longer half life, around 20-30 hours. "Long R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substition of an Arg(R) for the Glu(E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. This analog of IGF-1 has been produced with the purpose of increasing the biological activity of the IGF peptide."

"Long R3 IGF-1 is signifacantly more potent than IGF-1. The enhanced potency is due to the decreased binding of Long R3 IGF-1 to all known IGF binding proteins. These binding proteins normally inhibit the biological actions of IGF’s."

It is also not as expensive since a media grade version is available which is sufficient for bodybuilding use. There is also a receptor grade available but it is VERY expensive and the only noticeable difference between the two would only be able to be noticed in a laboratory setting. The price on the black market for Long R3 IGF-1 can be seen anywhere from $300-$500 per milligram depending on the source, be wary of black market ******s of any IGF since it is a VERY difficult item to obtain. As mentioned IGF is a research product and is only available from a few laboratories in the world and is only available to research companies and biotechnology institutions. For the rest of this article when I say IGF I am now referring to Long R3 IGF-1 for simplicity sake.

Any form of IGF is ONLY supplied in a lyphosized form, which means a dry powder state. NEVER PUCHASE PRE-DILUTED LIQUID IGF!!!! There is no such product made anywhere in the world and even if there were real IGF ever present in the vial it would all be dead by the time you receive it. IGF is a very delicate peptide and must be diluted by yourself, where you have access to a refrigerator and freezer. There has also been a lot of talk by certain sources claiming to have IGF made by the Eli Lilly company, to clear things up Lilly is a pharmaceutical company and as stated IGF is a research drug and has not yet been approved, Lilly does not and never has manufactured research drugs for retail sale.

The dilutents you will need for the IGF are a weak concentration of hydrochloric acid and a sterile buffer(sterile water or bacteriostatic water) the procedure for diluting the IGF is not very difficult, the dilutents can be obtained from most local chemical suppliers and a good source of IGF would also be able to supply the necessary dilutents.

The most effective length for a cycle of IGF is 50 days on and 20-40 days off. The most controversy surrounding Long R3 IGF-1 is the effective dosage. The most used dosages range between 20mcg/day to 120+mcg/day. IGF is only available by the milligram, one mg will give you a 50 day cycle at 20mcg/day, 2mg will give you a 50 day cycle at 40mcg/day, 3mg will give you a 50 day cycle at 60mcg/day, 4mg will give you a 50 day cycle at 80mcg/day and so on. The dosage issue mainly revolves around how much money you have to spend, plenty of people use the minimum dosage of 20mcg/day and are happy with the results, and in fact several top bodybuilders use the 20mcg/day dosage and are pleased with the results. IGF is most effective when administered subcutaneously and injected once or twice daily at your current dosage. The best time for injections is either in the morning and/or immediately after weight training.

Another frequently asked question of IGF refers to the real world results, in terms of pure weight gain don’t expect to gain 5 lbs. a week like you may off of anadrol or a similar steroid. The only weight you will gain from IGF use is pure lean muscle tissue, with steroids most of the weight gained is water weight. With an effective dosage you can expect to gain 1-2 lbs of new lean muscle tissue every 2-3 weeks and these effects can be increased with the use of testosterone, anabolic steroids, and insulin use. Increased vascularity is also very common, people report seeing veins appear where they never have before. And yet another effect reported is the ability to stay lean while bulking with heavy dosages of steroids and TONS of food while on an IGF cycle, this is perhaps the most pleasing effect. Increased pumps are also noticeable almost immediately, the pumps can almost become painful, pumps are even noticeable when doing cardio.

Overall, IGF is a very exciting drug due to its ability to alter ones genetic capabilities. If you can find a trustworthy source and you use it correctly it can be a VERY useful tool in your bodybuilding drug arsenal.

HGH Information

February 25th, 2008

Rating: (1 being the lowest, 5 being the highest)
Strength-4
Weight Gain-4
Fat Loss-4
Side Effects-2
Keep Gains–4

Side Effects:
Hypoglycemia- due to lowered insulin levels.
Aromeglia- (abnormal bone growth) GH does not cause it, but if you are
predisposed to it, it will speed it up.
GH gut- if predisposed and taking large doses of GH
Carpel Tunnel Syndrome
Soreness in Joints

Benefits of GH:
New Muscle Cells
Mood Enhancement
Smoothing and improving the skin
Leanness, it is a potent fat burner
Joint and ligament strengthening

Where to Inject, How, and How to Make:
You can site inject anywhere you can reach the subcutaneous layer. Pinch the
flesh and pull back, then insert the needle in the "pocket" underneath. Doesn’t
absorb quick enough if you inject into the adipose tissue. Do not inject
intra-muscular, though it can be done, it is not recommended. GH is a site
injection, where it is shot is where it will burn the most noticeable fat. Most
people do it in the stomach since that is a typical sub q shot with most of the
fat being in that area. GH should be kept in a fridge; freezing will destroy the
GH. On your kit it probably says to use the kit in 18-24 hours, remember these
are for AIDS patients, not bodybuilders or athletes. Mixing the GH can either be
done with sterile water or bacteriostic water. The kit with water will be fine
for 3 days in the fridge, even with the sterile water, but you should not take
this chance, rather you should use bacteriostic water and play it safe. This
will keep it fine for a couple of weeks. When mixing the GH, let the water slide
down the side as to not pulverize the GH wafer. Do not spray it directly against
the wafer with any force. Before reconstitution and even after GH is fragile!!!
Also once the water is injected into the bottle gently swirl the vial to
reconstitute, do not shake or swirl violently!!!!

Conversions:
1 ml = 1 cc -/+
100 units per 1 cc

6 mg = 18iu

1 ml = 18iu

.50 ml = 9iu

.25 ml = 4.5iu

Some people choose to only do it in cc’s but here is how you can do it in units
on a slin dart

5.5 = 1iu, so 2iu = 11 on a slin dart

Dose:

4 to 6 iu ed is sufficient. Most people take it 5 days on 2 days off at their
designated dosage. There is no reason or evidence why you cannot stay on for
various lengths of time; there is no need to go 5 on 2 off other than cost.
Considering that our natural production is only .5 to 1.5iu a day, this is still
a huge bump for the body. Research has shown that the body’s natural defense
systems render mega doses of GH ineffective, anyway. GH does not cause gains in
mass…it allows you to put on a great deal of lean mass in combination with
proper steroid and insulin use. The user before taking must know this. One or
two kits are not enough, you need at least 3 to make you happy, GH takes a while
to make its effects, but remember they are long lasting, what you see is what
you keep. It takes 6 to 8 weeks to notice a dramatic change in body comp using
GH on an ED or 5/2 split. Lighter doses for long periods of time are better than
large doses for short cycles. Like any other drug, the more you take the more
the benefits, but likewise also more risks. 4-6 iu is a standard dose but many
people take more, the most repulsing side effects happen at or beyond 12 iu a
day but like anything else it depends on your predisposition for it.

How to Stack:
GH is best taken in conjunction with insulin, anabolic steroids, and t3. Insulin
is extremely effective with GH, as anyone here who has tried it will testify.
This is because GH injections cause a down regulation of insulin sensitivity in
the body.
GH alone causes little growth of lean mass, however, when combined with insulin
and steroids (and IGF-1 if you can find it), the results can be down right
remarkable…esp. in the older bodybuilder. Start light with the
humulin…5iu…and work up 1 iu a day till you get use to it. 7 to 10iu in the
AM and 7 to 10 iu in the late afternoon, with split doses of GH is your best
bet. When splitting GH/insulin doses, I use mid-morning and late afternoon after
lifting…. both flat times in our natural GH production. The insulin overcomes
the insulin-resistance caused by exogenous GH supplementation. If you are scared
to take insulin thought, then Gh with Test and Glucophage is good. GH is good
for cutting if used alone. Glucophage allows for improved glucose and amino acid
absorption by the muscle tissue and does it safely. This is what you want. The
half-life of GH is only 2 hours so spread it out. Avoid bedtime injections since
we produce the bulk of our own GH in the first two hours of sleep. Since
exogenous GH suppresses this, you should not take it before bed. For best
results, use a 17aa oral during the cycle to stimulate the release of natural
insulin growth factors. I would run the test throughout. GH/insulin/test is the
proven synergistic combination.
It is also wise to preload with testosterone before starting GH if you are going
to do it. You should preload with the amount of time it takes for that
testosterone to kick in, since most of us take longer acting esters for
testosterone you should usually start taking the test 2 weeks before GH use.
Likewise, you can accommodate it to fit your needs; the key is for the test to
be kicking in the same time you are starting to run your GH. You can cycle you
steroids however you want to depending on your goals, if you are going for a
more massive look than you would run insulin for most of the cycle and use high
androgens, but if you are looking for additional leanness at the end of a cycle
you should stop the androgens and run a higher dose of GH or run less androgens.
T3 is also another substance that should be used during GH cycling since GH
lowers thyroid hormones. T3 should be used for shorter periods though, because
it can permanently alter the endocrine system. The magic of GH for men is the
ability to gain mass without fat or bloating when stacked properly with insulin,
and steroids. GH also makes for amazing improvements in skin…smoothes
wrinkles, burns stubborn spots of adipose tissue, gives that paper-thin contest
look…and also gives one a real mood lift, a feeling of well being.

Major Difference Between GH and Steroids:
Steroids can increase the size of your muscle cells, but cannot I repeat CAN NOT
increase the number of muscle cells in your body, which to start with is
governed by your genetics. However Growth hormone CAN increase the number of
muscle cells in your body, which goes beyond genetics.

Half-Life of GH:
Exogenous (injected) GH has a "half-life" of approximately 2 hours . . . a
4-hour period of activity during which there is a suppression of naturally
produced GH.

GH Naturally Produced:
We release the most of our naturally produced GH during the first two hours of
deep sleep…you may take a little time to adjust…. your body thinks you
should be in bed when that big influx hits. It is good to take a nap, that’s
when you grow anyway. It always helps to take naps after workouts and injections
everyday.

GH Causing Acromeglia:
Acromeglia is a disease…you either have it or you don’t. Supplementing GH will
not cause it. Persons suffering from acromeglia, like Andre the Giant, lack the
natural defense mechanisms of the body to regulate the production and effects of
GH secretion in he pituitary. It is well established in the medical literature
that exogenous GH will not cause the disease…. of course it would worsen the
condition in those who had it.

GH Gut: Myth or Reality?:

Some researchers claim that any gains in weight experienced by subjects using GH
alone was due to growth of internal organs and connective tissue, which could
cause some problems. Most studies do not agree with this theory and consider "GH
gut" to be a myth. Some people are allergic to synthetic test, this is something
you have to find out for yourself. Some people also feel intestinal discomfort
from time to time, if so take it down to one item at a time to see what is
causing you discomfort; creatine, glutamine, protein products, orals, and dirty
gear have all been known to cause this, so find the problem early.

GH and IGF-1:
Perhaps the most relevant effect of IGF-1 is the ability of IGF-1 to increase
protein synthesis by increasing cellular mRNA formation (mRNA makes protein) as
well as increasing uptake of amino acids. This effect on protein synthesis can
lead to increased lean mass. The research indicates that this effect is
dependent on GH presence as well. So IGF-1 alone does not promote such effects.
Nor does GH. It appears the combination of the two most consistently lead to
increased protein synthesis.

GH and IGF-1 are negative regulators of GH release so an increase in either
(from a GH injection) reduces the secretion of GH. IGF-1 is very difficult to
obtain in a useable condition…. it must be handled very gently and have bee
kept at a rather precise temperature at all times. One can stimulate IGF
production through the use of an oral steroid during cycle. Dbol, for example,
causes a rather extensive release of IGF during the first pass through the
liver.

Latest study by Yarashevski - with GH alone…8 to 12% change
in lean body composition. 6% increase in muscle mass.

How Long Should Different Steroids be Used?

February 25th, 2008

We regularly receive questions here at SE, along the lines of “how long should I run Equipoise for?”, or “how long should a cycle containing Testosterone Enanthate last?” These are important questions, and I will focus on oil based injectable steroids, such as Eq and Testosterone Enanthate, shortly. But first (and briefly) how about orals, and questions like “how long should I use Dianabol if I want to kick start my cycle?”

Most orals are without doubt best used for short periods. Dianabol is an example of an oral that works very well to kick start a gaining cycle containing slow acting injectables, while oral Winstrol (Stanozolol) might add additional hardness and tightness in the final four weeks of a cutter. Orals like Dianabol and Winstrol don’t need to be used for long in order to work well because of they are relatively strong, and because they have a very short half life. (The half life being the time it takes for a drug, after administration, to decrease in effectiveness by 50%.) The half life of Dianabol is just 4.5 hours, hence the need to split up the daily dosage – it builds up inside the body, and then gets out again fast.

It is a good thing that these orals work like this, because way they are altered to enable them to pass through the liver (they are 17 alpha-alkylated) causes them to raise liver enzymes to an unhealthy level if they are used for longer than four weeks (six weeks max). Anavar and primobolan are exception because they are milder, so even though that have a short half life they are best used for longer periods (8 weeks at a high dosage, or more like 12-16 weeks at average dosages). (Anavar is not harsh on the liver, and primobolan may not produce any liver toxicity at all.)

Now for oil based injectable steroids, and many of these need to be used for relatively long periods for best effect. Specifically, a slow acting steroid like Equipoise (Boldenone Undecylenate) requires time to build up in the body, very gradually over a period of weeks. Use your Eq for just six weeks and you might obtain some benefit, but for optimum effect you need to be on for at least twice that long.

But how do we know how long we need to use oil based injectable steroids, for best results? Well, we need to look at each drug’s half life. It is possible, once we know a steroid’s half life, to do a series of calculations in order to determine, with considerable accuracy, the levels of the drug that would be in our blood from week to week. We’d be able to represent this on a graph, to see how the amount of a drug (such as Eq) in the body steadily increases in the early period of administration, before reaching a peak later. (For those interested, take a look at this post by our good friend J-Rod: http://www.steroidencyclopaedia.com/…ad.php?t=61489)

But we can make like easy! Fortunately there is simple rule that can be followed for oil based injecable steroids, using the half life: the number of days that make up the half life will be equal to the minimum number of weeks that the steroid should be used for best results. So, some examples:

1. The half life of Testosterone Propionate and Drostanolone Propionate is 4.5 days, and obeying this rule we would need to run either of these steroid for 4.5 weeks for best results. Personally I like to run propionate for 6-10 weeks, but a 4-5 week “SHIC” cycle can produce good results.
2. The half life of testosterone enanthate is 10.5 days, so a cycle containing enanthate should not, for best effect, last less than 10 weeks.
3. Finally, Equipoise, because of its slow acting undecylenate ester, has a half life of 16 days. Many people will end a 12 week Eq cycle feeling satisfied, but on the other hand it is agreed by many that Eq is unusual in the sense that it comes into its own when cycles are extended to 16 weeks. (Note: the half life of Nandrolone Decanoate, or “Deca”, is 15 days, so again, a longer cycle is warranted.)

Since we are all respond to steroids differently, and have different goals, each of us needs to make a personal decision about how long we will be on cycle. My recommendation for people wishing to maintain their natural testosterone production is to take as much time off between cycles as possible, and to keep cycles as short as is feasible, without undermining outcomes. Why? Because the more time you spend on cycle, in a “shut down” state, the more likely it is that your natural hormone production will be impaired. Your hypothalamus will get lazy and stop making as much GnRH and/or your pituitary will get lazy and stop making as much LH and FSH – without sufficient LH and FSH your testes cannot make sufficient testosterone (or sperm).

Here it is also worth considering that long acting steroids take a while to gradually leave your system, during which time they will keep your natural testosterone firmly shut down. So, I’m afraid a 10 week cycle containing Testosterone Enanthate can easily continue to effect your natural production for 6 weeks or more after your last injection. First-hand experience has proven this to me: I’m on trt so I have no natural test at all. In 2006 I was supposed to be using 7.5g testogel per day, but I wanted to use 250mgs testosterone per week instead to help me harden up. I was still doing 250mgs test enanthate per week when my doctor decided to check my testosterone level that summer. I knew I would be way above the normal level my doctor was looking for. So, I came off everything (took no form of test) for a full 6 weeks prior the blood test. When I got the results it turned out that my testosterone was in the upper half of the normal range, after 6 WEEKS on nothing! Remember, I had NO natural test, so it must have been residual enanthate.

So, shorter cycles using faster acting steroids that exit the system faster, like propionates, may be better suited to people whose priority is to look after their natural production. On the other hand, people like myself who are spared this concern, because they are on testosterone replacement therapy, may prefer to enjoy their freedom to indulge in longer cycles – perhaps at lower dosages so that they don’t incur side effects associated with excessive steroid use. I really enjoy longer cycles, which at low doses can produce quality gains, and hardness, with minimal side effects.

-Samson

Training Psychology- Strive but don’t Demand

February 21st, 2008

Training Psychology – Strive but don’t demand.

Do you feel that you need to achieve your bodybuilding and fitness goals? Do you demand success, and do you have to have an impressive physique?

Well, it is good to strive to improve. It gives us meaning, purpose, and helps us feel good about yourselves. A good physique (as they say) adds life to years and years to life. But to need or demand success, as if self-worth depends upon it, is unhealthy.

As a psychological therapists I regularly encounter individuals who measure their self-worth according to their successes. They have to succeed, or they’re nothing. This is highly counterproductive because setbacks and failures leave them feeling crushed, inadequate, and as if there is just no point trying again.

Now demanding realistic success in bodybuilding isn’t always a problem, at least for those of us who are patient, reasonable, know what we’re doing. But what happens if/when we get a health problem, or an injury. Or perhaps we just misjudge things and finish the winter with our abs buried too deep beneath layers of fat. What then? Well, people who have really demanded success are likely to refuse to accept the situation, and get angry. Or they’ll be distracted while they ruminate on their personal inadequacies and failings, rather than doing anything proactive about the problem. Some people will panic, and go to extremes – too much or too little food, overtraining, or too much AAS.

So what’s the solution?

A guy called Albert Ellis (a famous psychologist and author) has said that we should try preferring instead of demanding, and rating our performance critically without rating ourselves. And it works. Someone that might PREFER to be at 10% body fat by the summer will not be crushed if they miss the target. Also, if they can rate their performance without rating and berating their whole self they will not be disabled by a sense of inadequacy. They will be problem centred, not self-centred, thinking “what can I learn from this valuable experience, and what new goals can I set?”, rather than “why am I so useless?”.

So, in summary, prefer, don’t demand; accept yourself, and however critically you rate your performance don’t rate yourself. This way you will stay positive, and achieve more. I know it works for me, and since I’m naturally a perfectionist I know I need to work at maintaining this kind of mental attitude in order to stay sane!

SAMSON.

Why one should wait until genetic potential has been reached

February 5th, 2008


For some it’s about pride and paying dues. Many have shed sweat and blood,persevered
through injury and personal sacrifice to build a physique few people will ever achieve.
It’s disconcerting to see a newbie walk in, take a few pills and then believe they are on the same level.
Hard core lifting is more than just knowing and taking the right pharmacology.

For most of us it’s a genuine concern for the newbie.
It takes more than gear to get exceptional results.
Before starting you should know your goals…are you looking to increase your strength, improve your looks, become famous, help your career, improve health, improve your
self-esteem, get big, get approval or for protection (physical or mental)?
The answer to that question determines the paths that are appropriate for you. Every BODY is different.
Do you know how your body acts and reacts?
How many calories does it take for you to maintain?
What food and feeding schedule can you tolerate?
How much water do you need to drink?
How much sleep do you need and how much good sleep can you get?
What parts of your body respond to higher reps?
What parts respond better to lower reps?
How many sets give you the best results?
What split works best?
How many rest days do you need?
What medical conditions do you have to adjust for?
What exercises work for you and which ones don’t?
Do you know how to treat your injuries?
Do you know how tell if you’re injuring yourself?

Then there are the things that only time and experience can give you:
The skill of using dedication and determination to achieve long term goals.
The knowledge that you can push yourself past limits, some you didn’t even know you had.
The experience and knowledge on how to use the equipment properly.
The strength to adhere to STRICT form during your lifts.
The strength to not give into ego and risk hurting yourself.
The strength to adhere to a training program.
The knowledge to know when its time to back off and the knowledge to know when to press on.
The strength to acknowledge your weaknesses and the wisdom to adjust for them.
The knowledge and respect of the dangers of impatience.

Additionally, time in the gym gives your bones, tendons and ligaments a chance to strengthen in order to handle the loads additional muscle will require.

By taking the time to learn what your body requires to grow, learning your limitations and
strengths, identifying your true goals and developing the skills in the weight
room you give yourself the best chance to use steroids successfully. If you don’t do this prep work you put yourself at risk.
By not knowing your body, it’ll take you longer to realize you need to adjust your dosages.
Failing to eat, drink and rest properly will limit your gains.
A lack of dedication and determination will waste your effort. An ill prepared body is more prone to soft tissue damage. An ill-informed user is far more likely to use steroids that are wrong for the wanted goal.
A person with a weak ego will put themselves at greater risk in and out of the weight room. An inexperienced lifter will be slower to recognize the positive and negative
effects of their steroids and not know how to make the appropriate adjustments.
An ill-informed lifter will waste a ton of money and possibly a portion of their health.
Steroids offer benefits and risks.
Surprisingly little is truly known about how they really work, their interactions and their long-term effects.

If a ‘newbie’ takes the time to develop their base and their knowledge, they have a high chance of successfully using steroids to achieve their goals.

If they take this time they will be able to take pride in knowing that it really
was them that achieved their goals, not what was in the pill or in the
syringe.
One thing is certain…you know less than you think you
know. (And that’s true for all of us.)

Personal Experience about Genetic Potential and AAS

February 5th, 2008
Genetic Potential and AAS

I know we have a sticky on the subject with scientific evidence and such, but i thought i would share my personal background into this discussion.

As you are all aware, i have been a memeber here for 2.5yrs now and have even been giving the honor being chosen as a VIP for SE, and though i have SE’s staff to thank for this gift, i have to thank all the members as well, because it if wasn’t for you guys, we would not be there!

A few of you know some history behind me and a bit of my background, but i thought i would dig deeper into my past to hopefully help you as newbies understand the reasoning why we as the SE staff recomend you not start using AAS until "Your Genetic Potential" has been reached.

I am 30 yrs old and have been in sports my whole life. I started playing soccer (that’s football for my Limey brothers, Blade and Samson (great guys BTW) at 4yrs old. You kow the fun to watch while the whole field looks like a bee colony all around the ball with now mind to actual positions. I played soccer through high school and loved it, but then i started wrestling (BAseball as well in the off season) and fell in love with it. Mind you my freshman year i wrestled in the 103lb class, 112 both sophmore and junior years and 119 my senior year. Due to my love for wrestling and natural ability i was sent to Oklahoma state every summer for Freestyle camps to help make me better, which it did taking state my last two years (greco ramon). I lifted weights for strength and conditioning all through high school and then had my first go with gear after the season with 10ml only of Test Cyp. It put 12lbs of muscle on my in a months time and it was great. Well i also got into drugs (Coke, Weed, and Ecstasy during school still) and blew my scholarship to Oklahoma. So i started working off shore rough necking and working the derricks (mind you i am from Louisiana). Money was great and i did a bit of juice here and there, mind you no sense or understanding to what i was doing just injedction it into my body, but yes i got bigger, not much but loooked and felt better. Now i never ate like i was supposed to because i had no idea. But what was told to me by others whow did was to buy some "747". What is 747 you ask, well it’s this nasty ass thick black pure vitamin shit for horses (same place i got my 3ml darts with 21g pins. Yes 21g pins in the ass, and they did not feel good.

So at 25-26 i decided to try it again and looked online for supps and bought stuff, sust of all things and ran a few cycles that i found on various sites and did gain weight, but still clueless. And then a miracle happened, i stumbled onto SE. I was only looking for a reutable supplier and a link for SE popped up and i joined (reluctantly i might add), but found my home. The members never judged me and i started reading learning and started saving things on my external hard drive to look up frequently to educate myself. Now i have greatly educated myself on different steroids, ancilleries and how and why they work (key to making the cycle right for you). I have also learned that DIET is the key to all, which i had no idea.

Well here i am with a quite a few cycles under my belt and the latest being very succesful and learning so much about them and how they effect me personally (PERSONALLY). So when i share with you guys, this advise is from my personal experiences.

Now to share with you with what i am trying to explain to you guys why you should wait. I have not run a cycle in almost a year now, and i went to get my blood work done before i start my next one here very soon. Well the Doc says that my levels are on the low side especially due to my age (30) just above 210ng/dl. Now the Dr. and i talked about, and yes he is well aware of my lifestyle. He asked no questions and i have to tell him no lies j/k. But he understands. He told me that TRT is going to a possibilty here very soon in my life, and i am only 30.

So what i am getting at here fellas is that that yes, you may be 21 and say one cycle may not hurt me, how certain are and are you really willing to take the chance? Are you willing to have to be on HRT or TRT for the rest of your life and stick yourself with a needls for the next 30-50 years? So when we say that we can help you reach your goals safelt and with out AAS, we are very sincere. We don’t want to see you guys get hurt, and mybe not now, but later in life and the rest of it.

So please do not take my life experiences with a grain of salt and please understand the method to the madness.

Thanks SE,

J-ROD